Tuesday, September 23, 2014

Leukoplakia of tongue

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Leukoplakia of tongue is very common in India because of rampant use of tobacco products and poor orodental hygiene.


How do we treat Leukoplakia?
Leukoplakia is a potentially malignant Disorder
Other lesion is erythroleukoplakia, which is more sinister

Incidence off oral cancers is 50-100 times higher in Leukoplakia.
The progression is difficult to predict.
In whom  and when cancer develops is unpredictable.

And how we do prevent progression of Leukoplakia to cancer?

•Smoking cessation • Moderation of alcohol use • Diet with adequate antioxidants • Improve oral hygiene I Trauma/ eliminate candida 'Surgical excision of high risk lesions • Surveillance • • 


Grade of dysplaia is important
Anatomical location has prognosis value.
Ploidy analysis has prognosis value.

Colour
Location
Dysplaia
Ploidy

Since most of leukoplakia are asymptotic the intervention objective is to prevent malign transformation

Chemoprevention trial
The COCHRANE COLLABORATION is gold standard

Electronic cigarettes is not therapeutic option
DRINKSMETER
To identity weekly alcohol abuse.
Improve diet
Anything yellow




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